hrp0082p1-d2-124 | Fat Metabolism & Obesity (1) | ESPE2014

A Dual Role of Fetuin A on Cardiovascular Risk in Obese Children and Adolescents

Wiegand Susanna , Buermann Mareike , Ernert Andrea , Briese Silvia , Bau Ann-Madeleine , Krude Heiko

Background: Cardiovascular diseases are most relevant for morbidity and mortality in obese patients. Because metabolic complications already start in childhood obesity one may expect an early manifestation of cardiovascular disease in this group as young adults. In adults fetuin A was shown to promote adipocyte inflammation and metabolic syndrome and subsequently vascular damage.Objective and hypotheses: We evaluated the role of fetuin A in the vascular ...